Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | GBA1 | P04062 | 6/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20588490 | 0.98 | SLC9A1 (0.38) | SLC9A1SMPD1TBXAS1KDRGBA1 | |
| SCHEMBL3739734 | 0.71 | FABP4 (0.39) | TBXAS1 | |
| SCHEMBL293470 | 0.68 | TBXAS1 (0.34) | SLC9A1SMPD1TBXAS1KDRTLR8 | |
| SCHEMBL2470467 | 0.67 | TBXAS1 (0.37) | SMPD1TBXAS1KDRTLR8 | |
| SCHEMBL16526395 | 0.65 | SMPD1 (0.51) | SLC9A1SMPD1GBA1 | |
| SCHEMBL960665 | 0.65 | TBXAS1 (0.40) | SMPD1TBXAS1KDRTLR8 | |
| SCHEMBL959796 | 0.65 | TBXAS1 (0.40) | SMPD1TBXAS1KDRTLR8 | |
| SCHEMBL233016 | 0.65 | MEN1 (0.65) | SLC9A1SMPD1TBXAS1KDR | |
| SCHEMBL16969284 | 0.64 | KDR (0.37) | SMPD1TBXAS1KDRTLR8 | |
| SCHEMBL20915328 | 0.64 | MEN1 (0.62) | SLC9A1SMPD1TBXAS1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208015-B2 | Aryl-triazolyl pyridines as pest control agents | BAYER ANIMAL HEALTH GMBH (DE) | 2019-02-19 | — | — | US | disclosed |
| US-20180369262-A1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | TETARD, INC. | 2018-12-27 | — | — | US | disclosed |
| EP-2362727-B1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | CEMPRA PHARMACEUTICALS INC (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9901592-B2 | Methods for treating resistant diseases using triazole containing macrolides | CEMPRA PHARMACEUTICALS, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| EP-3169674-A1 | ARYL-TRIAZOLYL PYRIDINES AS PEST CONTROL AGENTS | Bayer Animal Health GmbH (DE) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016008830-A1 | ARYL-TRIAZOLYL PYRIDINES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-21 | — | — | WO | disclosed |
| US-20150105339-A1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | TETARD, INC. | 2015-04-16 | — | — | US | disclosed |
| US-8796232-B2 | Methods for treating resistant diseases using triazole containing macrolides | CEMPRA PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-20110201566-A1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | CEMPRA PHARMACEUTICALS, INC. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180369262-A1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | LIPA, PNLIP, LIPC | SLC9A1 2887/4885SMPD1 498/4885TBXAS1 1514/4885 |
| US-20110201566-A1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | LIPA, PNLIP, LIPC | SLC9A1 2887/4885SMPD1 498/4885TBXAS1 1514/4885 |
| US-20150105339-A1 | METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES | LIPA, CEL, TREH | SLC9A1 3364/4885SMPD1 629/4885TBXAS1 986/4885 |
| US-10208015-B2 | Aryl-triazolyl pyridines as pest control agents | PTMS, TYR, PDXK | SLC9A1 4780/4885SMPD1 2337/4885TBXAS1 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.