SCHEMBL2059535

SCHEMBL2059535

F[C](F)c1ccc([C](F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
CES2 O00748 4/20 0.35
CES1 P23141 4/20 0.35
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
LMNA P02545 2/20 0.30
HPGD P15428 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MAPT P10636 2/20 0.30
HTT P42858 2/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
SRD5A2 P31213 1/20 0.30
GFER P55789 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17289141 0.86 CES2 (0.55) CES2CES1CA1CA2ESR1
SCHEMBL17288654 0.86 MAPT (0.53) TP53TSHRCES2CA1CA2
SCHEMBL16798463 0.83 CES2 (0.52) TSHRCES2CES1CA1CA2
SCHEMBL7932812 0.83
SCHEMBL17288381 0.83 ALDH1A1 (0.52) CES2CES1CA2LMNAHPGD
SCHEMBL17996528 0.83 TPMT (0.50) CA1CA2
SCHEMBL8612855 0.83 MAPT (0.50) TP53TSHRLMNAHPGDMAPT
SCHEMBL17996542 0.83 CES2 (0.52) TSHRCES2CES1CA1CA2
SCHEMBL188438 0.81
SCHEMBL17288863 0.78 PLK1 (0.52) TSHRLMNAHPGDMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372312-B1 Non-symmetrical dibenzodithienothiophene compounds XEROX CORPORATION (US) 2013-02-12 US claimed
US-20110227055-A1 PROCESS FOR THE PREPARATION OF ORGANIC ELECTRONIC DEVICES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-09-22 US claimed
US-7842942-B2 Organic semiconducting layers MERCK PATENT GMBH (DE) 2010-11-30 US claimed
EP-1687830-B1 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS MERCK PATENT GMBH (DE) 2010-07-28 EP claimed
EP-1340270-B1 FIELD EFFECT TRANSISTORS AND MATERIALS AND METHODS FOR THEIR MANUFACTURE MERCK PATENT GMBH (DE) 2007-01-03 EP claimed
US-11882710-B2 Thin-film transistor comprising organic semiconductor materials FLEXTERRA, INC. (US) 2024-01-23 US disclosed
US-11681236-B2 Method for in-situ dynamic protection of a surface and optical assembly CARL ZEISS SMT GMBH (DE) 2023-06-20 US disclosed
US-11345778-B2 Organic dielectric materials and devices including them FLEXTERRA, INC. (US) 2022-05-31 US disclosed
US-11196005-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2021-12-07 US disclosed
US-20210257568-A1 A Thin-Film Transistor Comprising Organic Semiconductor Materials USINVEST LLC 2021-08-19 US disclosed
EP-3664171-B1 A THIN-FILM TRANSISTOR COMPRISING ORGANIC SEMICONDUCTOR MATERIALS FLEXTERRA INC (US) 2021-05-12 EP disclosed
EP-3740523-A1 ORGANIC DIELECTRIC MATERIALS AND DEVICES INCLUDING THEM Flexterra, Inc. (US) 2020-11-25 EP disclosed
US-20110227055-A1 PROCESS FOR THE PREPARATION OF ORGANIC ELECTRONIC DEVICES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-09-22 US disclosed
US-20110175089-A1 Dielectric Materials and Methods of Preparation and Use Thereof FLEXTERRA, INC. 2011-07-21 US disclosed
WO-2011088343-A2 DIELECTRIC MATERIALS AND METHODS OF PREPARATION AND USE THEREOF POLYERA CORPORATION (US) 2011-07-21 WO disclosed
US-7948016-B1 Off-center deposition of organic semiconductor in an organic semiconductor device 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-24 US disclosed
US-20100215836-A1 FERROELECTRIC MATERIAL AND METHOD OF FORMING FERROELECTRIC LAYER USING THE SAME UNIVERSITY OF SEOUL FOUNDATION OF INDUSTRY- ACADEMIC COOPERATION (KR) 2010-08-26 US disclosed
US-20100108999-A1 PROCESS FOR PREPARING AN ELECTRONIC DEVICE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) 2010-05-06 US disclosed
US-20100096679-A1 FET, FERROELECTRIC MEMORY DEVICE, AND METHODS OF MANUFACTURING THE SAME UNIVERSITY OF SEOUL FOUNDATION OF INDUSTRY- ACADEMIC COOPERATION (KR) 2010-04-22 US disclosed
US-5841005-A REACTING A DIHALO COMPOUND WITH A REDUCING AGENT IN THE PRESENCE OF A TRANSITION METAL CATALYST SPECIALTY COATING SYSTEMS, INC. 1998-11-24 US disclosed