SCHEMBL7932812

SCHEMBL7932812

[CH2]c1ccc([C](F)F)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059535 0.83 TP53 (0.35)
SCHEMBL17288654 0.71 MAPT (0.53)
SCHEMBL17289141 0.71 CES2 (0.55)
SCHEMBL147275 0.71
SCHEMBL17288935 0.69 ALDH1A1 (0.58)
SCHEMBL16798463 0.69 CES2 (0.52)
SCHEMBL17996528 0.69 TPMT (0.50)
SCHEMBL9615865 0.69 SRD5A2 (0.55)
SCHEMBL8612855 0.69 MAPT (0.50)
SCHEMBL3177448 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194620-B1 FOR MAKING POLYDIFLUOROCHLORO-PARA-XYLENE FILMS; THERMOSTABILITY DAISAN KASEI KABUSHIKI KAISHA (JP) 2001-02-27 US disclosed
EP-0856503-B1 Dichloro-tetrafluoro-[2,2]-paracyclophane, a process for manufacturing thereof and poly-alpha,alpha-difluoro-chloro-para-xylylene film prepared therefrom DAISAN KASEI CO LTD (JP) 2000-05-10 EP disclosed
EP-0856503-A1 Dichloro-tetrafluoro-2,2-paracyclophane, a process for manufacturing thereof and poly-alpha, alpha-difluoro-chloro-para-xylylene film prepared therefrom Daisan Kasei Co., Ltd. (JP) 1998-08-05 EP disclosed