Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059535 | 0.83 | TP53 (0.35) | MAPTHSD17B10TSHRTP53LMNA | |
| SCHEMBL23390994 | 0.77 | LMNA (0.48) | MAPTMEN1KMT2AMASP2PLAU | |
| SCHEMBL10493685 | 0.73 | MAPT (0.57) | MAPTMEN1KMT2AMASP2PLAU | |
| SCHEMBL10933735 | 0.73 | CYP19A1 (0.65) | MAPTMEN1KMT2AMASP2PLAU | |
| SCHEMBL17289141 | 0.71 | CES2 (0.55) | MEN1KMT2AESR1ESR2ACHE | |
| SCHEMBL8668012 | 0.71 | MAPT (0.53) | MAPTMEN1KMT2AMASP2PLAU | |
| SCHEMBL27981 | 0.71 | — | — | |
| SCHEMBL320609 | 0.71 | MEN1 (1.00) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL11359248 | 0.69 | MASP2 (0.44) | MAPTMEN1KMT2AMASP2PLAU | |
| SCHEMBL17996528 | 0.69 | TPMT (0.50) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998031689-A1 | NOVEL MIXED BENZENE ACID DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-07-23 | — | — | WO | disclosed |