Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 15/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18342799 | 0.81 | IDO1 (0.38) | IDO1MAPTKMT2A | |
| SCHEMBL16538309 | 0.77 | IDO1 (0.36) | IDO1ABCB11ADORA3ARCYP2D6 | |
| SCHEMBL16538494 | 0.76 | IDO1 (0.41) | IDO1ABCB11ADORA3ARCYP2D6 | |
| SCHEMBL16538202 | 0.76 | ALDH1A1 (0.31) | IDO1 | |
| SCHEMBL28145488 | 0.72 | IDO1 (0.38) | IDO1SLC6A2SLC6A4LMNACCKBR | |
| SCHEMBL18342952 | 0.69 | IDO1 (0.51) | IDO1KMT2A | |
| SCHEMBL16538371 | 0.69 | KMT2A (0.45) | IDO1ABCB11ADORA3ARCYP2D6 | |
| SCHEMBL4471183 | 0.69 | CCKBR (0.39) | IDO1SLC6A2SLC6A4S1PR1CCKBR | |
| SCHEMBL20301578 | 0.68 | IDO1 (0.35) | IDO1S1PR1CCKBR | |
| SCHEMBL21939387 | 0.68 | IDO1 (0.41) | IDO1LMNACCKBRKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689331-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190002402-A1 | IDO INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002402-A1 | IDO INHIBITORS | IDO1, IDO2, INMT | IDO1 1/4885ABCB11 4044/4885ADORA3 1665/4885 |
| US-10689331-B2 | IDO inhibitors | IDO1, IDO2, INMT | IDO1 1/4885ABCB11 4044/4885ADORA3 1665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.