Sugi Predict

Sugi Predict / Compounds / SCHEMBL20599655

SCHEMBL20599655

SCHEMBL20599655

CC(C)(C)OC(=O)N1CC(S(N)(=O)=O)C1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 1/20 0.49
▸ USP2 O75604 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ HPGD P15428 1/20 0.41
▸ PIK3CA P42336 2/20 0.39
▸ AKT1 P31749 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ GPR119 Q8TDV5 3/20 0.39
▸ RECQL P46063 1/20 0.39
▸ EPHX1 P07099 1/20 0.39
▸ CA12 O43570 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CA9 Q16790 1/20 0.38
▸ DDB1 Q16531 1/20 0.38
▸ CRBN Q96SW2 1/20 0.38
▸ NAMPT P43490 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20635222 0.89 NR1H2 (0.43) NR1H2USP2SMN1; SMN2HPGDPIK3CA
SCHEMBL57472 0.87 HPGD (0.47) NR1H2USP2SMN1; SMN2HPGDGPR119
SCHEMBL18247076 0.84 MEN1 (0.50) USP2SMN1; SMN2HPGDEPHX1MEN1
SCHEMBL18246716 0.84 MEN1 (0.50) USP2SMN1; SMN2HPGDEPHX1MEN1
SCHEMBL18246717 0.84 MEN1 (0.50) USP2SMN1; SMN2HPGDEPHX1MEN1
SCHEMBL4183086 0.84 NR1H2 (0.50) NR1H2USP2SMN1; SMN2HPGDGPR119
SCHEMBL626244 0.84 NR1H2 (0.50) NR1H2USP2SMN1; SMN2HPGDGPR119
SCHEMBL56404 0.83 HPGD (0.53) USP2SMN1; SMN2HPGDGPR119RECQL
Hydrochloric Acid SCHEMBL28063086 0.82 NR1H2 (0.49) NR1H2USP2SMN1; SMN2HPGDPIK3CA
SCHEMBL20634422 0.82 NR1H2 (0.40) NR1H2USP2SMN1; SMN2HPGDGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894878-A Aromatic amide derivative and preparation method and application thereof 浙江海正药业股份有限公司 2025-04-25 — — CN disclosed
US-20250115591-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LTD (IE) 2025-04-10 — — US disclosed
US-11981667-B2 Sulfonamide carboxamide compounds INFLAZOME LIMITED (IE) 2024-05-14 — — US disclosed
WO-2024078569-A1 AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2024-04-18 — — WO disclosed
CN-111132974-B Sulfonamide carboxamide compounds 英夫拉索姆有限公司 2023-11-21 — — CN disclosed
US-11634390-B2 Agricultural chemicals GLOBACHEM NV (BE) 2023-04-25 — — US disclosed
US-11634390-B2 Agricultural chemicals GLOBACHEM NV (BE) 2023-04-25 — — US disclosed
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LTD (IE) 2023-02-02 — — US disclosed
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LTD (IE) 2023-02-02 — — US disclosed
US-11465992-B2 Sulfonamide carboxamide compounds INFLAZOME LIMITED (IE) 2022-10-11 — — US disclosed
US-20200361895-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2020-11-19 — — US disclosed
US-20200291003-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS SYGNATURE DISCOVERY LIMITED (GB) 2020-09-17 — — US disclosed
US-20200291003-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS SYGNATURE DISCOVERY LIMITED (GB) 2020-09-17 — — US disclosed
CN-111132974-A Novel sulfonamide carboxamide compounds 英夫拉索姆有限公司 2020-05-08 — — CN disclosed
EP-3645516-A1 HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS Janssen Pharmaceutica NV (BE) 2020-05-06 — — EP disclosed
CN-110914256-A Novel sulfonamide carboxamide compounds 英夫拉索姆有限公司 2020-03-24 — — CN disclosed
US-20190322627-A1 AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2019-10-24 — — US disclosed
WO-2019034686-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2019-02-21 — — WO disclosed
WO-2019008025-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2019-01-10 — — WO disclosed
WO-2019001420-A1 HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS JANSSEN PHARMACEUTICA NV (BE) 2019-01-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361895-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 NR1H2 357/4885USP2 2649/4885SMN1; SMN2 2674/4885
US-20190322627-A1 AGRICULTURAL CHEMICALS DDT, DHFR, AS3MT NR1H2 2908/4885USP2 1161/4885SMN1; SMN2 4480/4885
US-11981667-B2 Sulfonamide carboxamide compounds NLRP3, NOD1, PYCARD NR1H2 437/4885USP2 2788/4885SMN1; SMN2 2759/4885
US-20250115591-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 NR1H2 403/4885USP2 2264/4885SMN1; SMN2 2436/4885
US-20200291003-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 NR1H2 403/4885USP2 2264/4885SMN1; SMN2 2436/4885
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 NR1H2 389/4885USP2 2467/4885SMN1; SMN2 2558/4885
US-11465992-B2 Sulfonamide carboxamide compounds NLRP3, NOD1, PYCARD NR1H2 426/4885USP2 2672/4885SMN1; SMN2 2766/4885
US-11634390-B2 Agricultural chemicals DDT, DHFR, AS3MT NR1H2 2908/4885USP2 1161/4885SMN1; SMN2 4480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.