Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599658 | 0.94 | NPSR1 (0.38) | FFAR3NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2481439 | 0.73 | FFAR3 (0.42) | FFAR3NPSR1 | |
| SCHEMBL1928676 | 0.70 | — | — | |
| SCHEMBL873786 | 0.70 | FFAR3 (0.39) | FFAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL17425036 | 0.69 | — | — | |
| SCHEMBL17958 | 0.66 | NPSR1 (0.52) | FFAR3NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7739592 | 0.66 | ALDH1A1 (0.45) | FFAR3NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11094075 | 0.65 | FFAR3 (0.39) | FFAR3 | |
| SCHEMBL265557 | 0.65 | SMN1; SMN2 (0.45) | FFAR3ALDH1A1SMN1; SMN2 | |
| SCHEMBL28000867 | 0.65 | FFAR3 (0.39) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121363-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| EP-3645516-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | Janssen Pharmaceutica NV (BE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019001420-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-03 | — | — | WO | disclosed |