Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327634 | 0.95 | PTGS1 (0.42) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1426485 | 0.81 | LMNA (0.41) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3152073 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL20047912 | 0.80 | SMN1; SMN2 (0.35) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15978110 | 0.79 | MMP1 (0.52) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL14660249 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL20048140 | 0.78 | POLB (0.51) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9363498 | 0.76 | ALDH1A1 (0.38) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL2851785 | 0.75 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL20048230 | 0.74 | MAPT (0.45) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423034-A1 | ABUSE-DETERRENT PHARMACEUTICAL COMPOSITION | G.L. Pharma GmbH (AT) | 2019-01-09 | — | — | EP | disclosed |
| CN-1863513-A | Abuse-proffed dosage form | GRUENENTHAL GMBH (DE) | 2006-11-15 | — | — | CN | disclosed |
| CN-1863514-A | Abuse-proffed dosage form | GRUENENTHAL GMBH (DE) | 2006-11-15 | — | — | CN | disclosed |
| CN-1179418-A | Novel cyloalkyl derivatives as inhibitors of bone resorption and vitronectin receptor antagonists | HOECHST AG (DE) | 1998-04-22 | — | — | CN | disclosed |