Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607282 | 0.95 | SMN1; SMN2 (0.41) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL14660249 | 0.83 | ALDH1A1 (0.44) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL1426485 | 0.80 | LMNA (0.41) | MGLLKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL28226624 | 0.79 | PTGS1 (0.46) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL10347768 | 0.79 | GBA1 (0.43) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL20047912 | 0.75 | SMN1; SMN2 (0.35) | CNR1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3152073 | 0.75 | SMN1; SMN2 (0.42) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL9363498 | 0.75 | ALDH1A1 (0.38) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL11103713 | 0.75 | ALDH1A1 (0.46) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL15978110 | 0.74 | MMP1 (0.52) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6909012-B2 | Diflunisal esters and related compounds | UNIVERSITY OF QUEENSLAND (AU) | 2005-06-21 | — | — | US | disclosed |
| US-20030220497-A1 | Novel diflunisal esters and related compounds | THE UNIVERSITY OF QUEENSLAND | 2003-11-27 | — | — | US | disclosed |
| US-6593365-B1 | Method for treating and/or controlling thrombosis in a mammal, comprising administering to a mammal in need thereof an effective dosage of a compound having the formula: | THE UNIVERSITY OF QUEENSLAND (AU) | 2003-07-15 | — | — | US | disclosed |
| WO-1998046234-A1 | NOVEL DIFLUNISAL ESTERS AND RELATED COMPOUNDS | THE UNIVERSITY OF QUEENSLAND (AU) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220497-A1 | Novel diflunisal esters and related compounds | HPGDS, ALOX12, ALOX15 | PTGS1 7/4885PTGS2 14/4885MGLL 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.