Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.31 |
| ▸ | PRKCG | P05129 | 3/20 | 0.31 |
| ▸ | PRKCB | P05771 | 3/20 | 0.31 |
| ▸ | PRKCA | P17252 | 3/20 | 0.31 |
| ▸ | PRKCH | P24723 | 3/20 | 0.31 |
| ▸ | PRKCI | P41743 | 3/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.30 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27891444 | 1.00 | TSHR (0.36) | TSHRTHRBDNM1PRKD3PRKCG | |
| SCHEMBL23045018 | 1.00 | TSHR (0.36) | TSHRTHRBDNM1PRKD3PRKCG | |
| SCHEMBL8849908 | 0.80 | — | — | |
| SCHEMBL28787471 | 0.80 | THRB (0.35) | TSHRTHRBDNM1 | |
| SCHEMBL7055968 | 0.69 | TSHR (0.42) | TSHRTHRBDNM1LMNA | |
| SCHEMBL27993585 | 0.69 | TSHR (0.42) | TSHRTHRBDNM1LMNA | |
| SCHEMBL18804467 | 0.69 | TSHR (0.42) | TSHRTHRBDNM1LMNA | |
| SCHEMBL8849259 | 0.69 | LMNA (0.30) | TSHRLMNA | |
| SCHEMBL4971685 | 0.69 | TSHR (0.42) | TSHRTHRBDNM1LMNA | |
| SCHEMBL7052841 | 0.69 | TSHR (0.42) | TSHRTHRBDNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2691464-B1 | MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS WITH IMPROVED ADHESION TO CONCRETE | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-01-09 | — | — | EP | claimed |