Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183057 | 0.86 | SMPD1 (0.48) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL28085585 | 0.81 | FFAR4 (0.49) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL20607764 | 0.79 | MAPK14 (0.43) | MRGPRX4NPC1FFAR1LMNAL3MBTL1 | |
| SCHEMBL2988197 | 0.79 | L3MBTL1 (0.56) | BRD4HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL31757763 | 0.79 | L3MBTL1 (0.56) | BRD4HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL20607776 | 0.79 | MRGPRX4 (0.39) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL20607789 | 0.77 | MRGPRX4 (0.44) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 | |
| SCHEMBL20607861 | 0.76 | MAPK14 (0.47) | MRGPRX4NPC1FFAR1L3MBTL1MAPT | |
| SCHEMBL5446276 | 0.76 | L3MBTL1 (0.53) | NPC1SMN1; SMN2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL1901206 | 0.76 | S1PR5 (0.55) | MRGPRX4SMPD1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971191-A1 | BORON-CONTAINING SMALL MOLECULES | Bill And Melinda Gates Foundation (US) | 2022-03-23 | — | — | EP | disclosed |
| CN-113563368-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-10-29 | — | — | CN | disclosed |
| CN-113321672-A | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-08-31 | — | — | CN | disclosed |
| EP-3423065-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2021-07-21 | — | — | EP | disclosed |
| CN-109195608-B | Boron-containing small molecules | 比尔及梅琳达盖茨基金会 | 2021-05-11 | — | — | CN | disclosed |
| US-10919916-B2 | Boron-containing small molecules | BILL & MELINDA GATES FOUNDATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BILL & MELINDA GATES FOUNDATION (US) | 2020-08-06 | — | — | US | disclosed |
| US-10611780-B2 | Boron-containing small molecules | BILL AND MELINDA GATES FOUNDATION (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190077814-A1 | BORON-CONTAINING SMALL MOLECULES | GATES FOUNDATION | 2019-03-14 | — | — | US | disclosed |
| EP-3423065-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077814-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | MRGPRX4 709/4885SMPD1 1318/4885HDAC1 1653/4885 |
| US-10919916-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | MRGPRX4 709/4885SMPD1 1318/4885HDAC1 1653/4885 |
| US-10611780-B2 | Boron-containing small molecules | BCL6B, BLVRB, BTD | MRGPRX4 709/4885SMPD1 1318/4885HDAC1 1653/4885 |
| US-20200247827-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BLVRB, BTD | MRGPRX4 709/4885SMPD1 1318/4885HDAC1 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.