Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395263 | 0.86 | PTGER1 (0.56) | FFAR4FFAR1L3MBTL1LMNAMAPT | |
| SCHEMBL31757763 | 0.86 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPTBRD4PTGER1 | |
| SCHEMBL2988197 | 0.86 | L3MBTL1 (0.56) | L3MBTL1LMNAMAPTBRD4PTGER1 | |
| SCHEMBL5446276 | 0.85 | L3MBTL1 (0.53) | L3MBTL1NPC1 | |
| SCHEMBL29284729 | 0.84 | LMNA (0.52) | LMNALRRK2PTGER1SMPD1HDAC1 | |
| SCHEMBL28085590 | 0.84 | PTGER1 (0.52) | NPC1MRGPRX4PPIAPTGER1 | |
| SCHEMBL28085734 | 0.84 | MTNR1A (0.46) | FFAR4L3MBTL1LMNAMAPTNPC1 | |
| SCHEMBL20954700 | 0.84 | MTNR1A (0.58) | L3MBTL1MAPTNPC1LRRK2HDAC8 | |
| SCHEMBL31032329 | 0.84 | RXRA (0.57) | MRGPRX4PPIALRRK2PTGER1 | |
| SCHEMBL28085676 | 0.83 | CFD (0.53) | FFAR4L3MBTL1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |