Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590855 | 0.99 | FKBP1A (0.37) | FKBP1A | |
| SCHEMBL24590933 | 0.90 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL20611422 | 0.90 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL24590913 | 0.89 | PLG (0.33) | FKBP1A | |
| SCHEMBL24590798 | 0.86 | FKBP1A (0.31) | FKBP1A | |
| SCHEMBL20612211 | 0.85 | CTSL (0.36) | — | |
| SCHEMBL24590828 | 0.85 | PLG (0.33) | FKBP1A | |
| SCHEMBL20611525 | 0.84 | ACE (0.36) | — | |
| SCHEMBL20611410 | 0.84 | CTSB (0.35) | FKBP1A | |
| SCHEMBL20612095 | 0.83 | FKBP1A (0.35) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038640-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2019-01-02 | — | — | EP | disclosed |