Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13596760 | 0.80 | ADRB3 (0.50) | ADRB3ADRB1ADRB2BCHECHRNB2 | |
| SCHEMBL25966351 | 0.76 | HTR4 (0.48) | FFAR4DCPS | |
| SCHEMBL20612865 | 0.72 | FFAR4 (0.44) | FFAR4 | |
| SCHEMBL25966329 | 0.72 | FFAR4 (0.41) | FFAR4DCPS | |
| SCHEMBL20612907 | 0.72 | FFAR4 (0.41) | FFAR4DCPS | |
| SCHEMBL20612937 | 0.72 | FFAR4 (0.42) | FFAR4DCPS | |
| SCHEMBL20613065 | 0.71 | BRD4 (0.46) | ADRB3ADRB1ADRB2FFAR4 | |
| SCHEMBL20612924 | 0.71 | PARP1 (0.46) | FFAR4 | |
| SCHEMBL25967371 | 0.71 | FFAR4 (0.43) | FFAR4 | |
| SCHEMBL11380697 | 0.71 | ADRB3 (0.68) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |