SCHEMBL20613624

SCHEMBL20613624

CCSc1cc(I)cnc1C(=O)CC

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17986659 0.86 ALDH1A1 (0.35) MAPTMEN1KMT2AAOC3
SCHEMBL23629353 0.81 MAPT (0.38) MAPTMEN1KMT2AAOC3
SCHEMBL20613611 0.81 HDAC3 (0.34) AOC3
SCHEMBL17986658 0.81 GABRA2 (0.39) MAPTMEN1KMT2A
SCHEMBL20613015 0.79 ALDH1A1 (0.34) MAPTKMT2A
SCHEMBL16834272 0.78 NPSR1 (0.42) MAPTMEN1KMT2A
SCHEMBL23963291 0.77 EGLN1 (0.34)
SCHEMBL20597380 0.75 KMT2A (0.31) MAPTKMT2A
SCHEMBL19297184 0.74 MET (0.32)
SCHEMBL19297158 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421475-B1 CONDENSED HETEROCYCLIC COMPOUND HAVING BONDED HETEROCYCLES AND SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAID INSECTICIDE NIHON NOHYAKU CO LTD (JP) 2021-12-29 EP disclosed
EP-3421475-A1 CONDENSED HETEROCYCLIC COMPOUND HAVING BONDED HETEROCYCLES AND SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAID INSECTICIDE Nihon Nohyaku Co., Ltd. (JP) 2019-01-02 EP disclosed