Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647193 | 0.80 | ACHE (0.54) | ACHEGAAKMT2AGRM5CHRM1 | |
| SCHEMBL15015222 | 0.77 | CHRM3 (0.76) | CHRM1CHRM3CHRM2 | |
| SCHEMBL15127537 | 0.77 | CHRM3 (0.76) | CHRM1CHRM3CHRM2 | |
| SCHEMBL14628097 | 0.76 | LMNA (0.50) | GAAKMT2AEPHX2CHRM3SMN1; SMN2 | |
| SCHEMBL15127544 | 0.76 | ACHE (0.49) | ACHEGAAKMT2AGRM5CHRM1 | |
| SCHEMBL470951 | 0.74 | ALDH1A1 (0.48) | ACHEGAAKMT2AEPHX2NPC1 | |
| SCHEMBL13504041 | 0.74 | HPGD (0.70) | ACHEKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4311676 | 0.73 | CYP2C9 (0.42) | KMT2ACHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL11282002 | 0.73 | ACHE (0.53) | ACHEGAAKMT2AGRM5CHRM3 | |
| Fluorobenzene SCHEMBL27670265 | 0.72 | ACHE (0.60) | ACHEGAAKMT2AGRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019003142-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-03 | — | — | WO | disclosed |