Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598038 | 0.89 | SCN10A (0.42) | MAPTCYP1A2CYP2C19NPC1TP53 | |
| SCHEMBL20597986 | 0.87 | MAPK1 (0.42) | MAPTCYP1A2CYP2C19NPC1TP53 | |
| SCHEMBL24187965 | 0.84 | MAPT (0.41) | MAPTCYP1A2CYP2C19NPC1TP53 | |
| SCHEMBL20619600 | 0.84 | SCN10A (0.42) | MAPTCYP1A2CYP2C19NPC1TP53 | |
| SCHEMBL20619496 | 0.84 | SCN10A (0.42) | MAPTCYP1A2TP53RAB9ASCN10A | |
| SCHEMBL24187976 | 0.76 | LMNA (0.43) | MAPTCYP1A2NPC1TP53RAB9A | |
| SCHEMBL17678702 | 0.76 | OGA (0.38) | — | |
| SCHEMBL17674350 | 0.76 | OGA (0.38) | PIK3CA | |
| SCHEMBL20618302 | 0.75 | MTOR (0.42) | MTORPIK3CAPIK3CGLMNASMN1; SMN2 | |
| SCHEMBL17674213 | 0.75 | ALOX15 (0.43) | MAPTTP53PKMMAPK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |