Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619600 | 0.88 | SCN10A (0.42) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL20619615 | 0.84 | SCN10A (0.37) | LMNAALDH1A1MAPTPDE4BTP53 | |
| SCHEMBL24187946 | 0.84 | BACE1 (0.37) | ALDH1A1MAPTPDE4BSCN10A | |
| SCHEMBL20620052 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9A | |
| SCHEMBL20619503 | 0.80 | HCK (0.38) | LMNAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL17845839 | 0.79 | OPRK1 (0.48) | LMNAVNN1 | |
| SCHEMBL17845850 | 0.79 | VNN1 (0.40) | LMNAALDH1A1SMN1; SMN2VNN1 | |
| SCHEMBL20619918 | 0.78 | SCN10A (0.41) | ALDH1A1SMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL20619910 | 0.76 | MAPT (0.41) | LMNAALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL20597986 | 0.76 | MAPK1 (0.42) | ALDH1A1SMN1; SMN2MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010882-A1 | DIHYDROQUINOXALINE AND DIHYDROPYRIDOPYRAZINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC, (US) | 2022-01-13 | — | — | WO | disclosed |