Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24187976 | 0.88 | LMNA (0.43) | SCN10AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20598038 | 0.87 | SCN10A (0.42) | SCN10AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20619615 | 0.87 | SCN10A (0.37) | SCN10AALDH1A1MAPTLMNAPDE4B | |
| SCHEMBL20619496 | 0.86 | SCN10A (0.42) | SCN10AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL24187946 | 0.86 | BACE1 (0.37) | SCN10AALDH1A1MAPTPDE4B | |
| SCHEMBL20597986 | 0.86 | MAPK1 (0.42) | SCN10AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20619910 | 0.84 | MAPT (0.41) | SCN10AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20620052 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTRAB9AL3MBTL1 | |
| SCHEMBL20619918 | 0.82 | SCN10A (0.41) | SCN10AALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20619503 | 0.82 | HCK (0.38) | ALDH1A1MAPTRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010882-A1 | DIHYDROQUINOXALINE AND DIHYDROPYRIDOPYRAZINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC, (US) | 2022-01-13 | — | — | WO | disclosed |
| WO-2019199908-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |