Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403861 | 0.79 | LATS1 (0.34) | — | |
| SCHEMBL2937347 | 0.76 | LMNA (0.46) | TUBB1MAPTMAPK1LMNAHTT | |
| SCHEMBL20620239 | 0.73 | PGK1 (0.42) | TUBB1 | |
| SCHEMBL12403870 | 0.72 | RAB9A (0.42) | MAPTALDH1A1MAPK1LMNAHTT | |
| SCHEMBL12403868 | 0.72 | TUBB1 (0.44) | TUBB1MAPK1LMNAHTTRAB9A | |
| SCHEMBL14432013 | 0.72 | GRM4 (0.44) | ALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL21966922 | 0.72 | MAPT (0.40) | MAPTALDH1A1LMNAHTTGAA | |
| SCHEMBL16173475 | 0.71 | CYP3A4 (0.43) | TUBB1MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL2001415 | 0.71 | LMNA (0.43) | TUBB1MAPTMAPK1LMNAHTT | |
| SCHEMBL29025170 | 0.71 | MAPK1 (0.41) | MAPTALDH1A1MAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689331-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-06-23 | — | — | US | disclosed |
| US-20190002402-A1 | IDO INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002402-A1 | IDO INHIBITORS | IDO1, IDO2, INMT | TUBB1 3174/4885MAPT 1988/4885ALDH1A1 707/4885 |
| US-10689331-B2 | IDO inhibitors | IDO1, IDO2, INMT | TUBB1 3174/4885MAPT 1988/4885ALDH1A1 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.