Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 3/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.60 |
| ▸ | SRC | P12931 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627046 | 0.87 | NTRK1 (0.63) | NTRK1FLT3KDRFGFR1SRC | |
| SCHEMBL20627653 | 0.82 | FGFR1 (0.71) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL19350885 | 0.82 | FGFR1 (0.57) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL19350947 | 0.82 | FGFR1 (0.61) | NTRK1FLT3FGFR1SRCALDH1A1 | |
| SCHEMBL20627783 | 0.80 | FGFR1 (0.68) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL20627506 | 0.80 | FLT3 (0.55) | NTRK1FLT3KDRFGFR1SRC | |
| SCHEMBL20627772 | 0.80 | FLT3 (0.55) | NTRK1FLT3KDRFGFR1SRC | |
| SCHEMBL23742244 | 0.79 | PSMB1 (0.69) | HRH3 | |
| SCHEMBL29623418 | 0.78 | FLT3 (0.63) | NTRK1FLT3KDRCDK2MAPK14 | |
| SCHEMBL19350961 | 0.78 | FLT3 (0.63) | NTRK1FLT3KDRCDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |