Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | FOS | P01100 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057921 | 0.87 | FOS (0.38) | PTGER1EPHX2PPARGALDH1A1MAPT | |
| SCHEMBL15057366 | 0.87 | EPHX2 (0.41) | PTGER1EPHX2PPARGALDH1A1MAPT | |
| SCHEMBL15057134 | 0.87 | PTGER1 (0.37) | PTGER1EPHX2PPARGALDH1A1MAPT | |
| SCHEMBL15057507 | 0.86 | EPHX2 (0.38) | PTGER1EPHX2PPARGALDH1A1MAPT | |
| SCHEMBL15058148 | 0.84 | ALDH1A1 (0.40) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15076167 | 0.83 | PTGER1 (0.52) | PTGER1 | |
| SCHEMBL15076243 | 0.83 | ALDH1A1 (0.40) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15076250 | 0.83 | PTGER1 (0.41) | PTGER1EPHX2PPARGALDH1A1MAPT | |
| SCHEMBL15057111 | 0.82 | MAOA (0.44) | EPHX2PPARGTSHRMAOAMAOB | |
| SCHEMBL15057792 | 0.82 | XDH (0.40) | EPHX2PPARGMAPTTSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |