Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 12/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | FOS | P01100 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058148 | 0.82 | ALDH1A1 (0.40) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15057343 | 0.82 | ALDH1A1 (0.41) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL20628799 | 0.82 | PTGER1 (0.39) | PTGER1HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL20628806 | 0.80 | ALDH1A1 (0.40) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15057507 | 0.74 | EPHX2 (0.38) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL22728618 | 0.73 | PTGER1 (0.39) | PTGER1 | |
| SCHEMBL15057775 | 0.73 | PLA2G4A (0.43) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15057366 | 0.73 | EPHX2 (0.41) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15057921 | 0.73 | FOS (0.38) | PTGER1ALDH1A1MAPTPKMTSHR | |
| SCHEMBL15057589 | 0.72 | PLA2G4A (0.42) | PTGER1ALDH1A1MAPTPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |