Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057237 | 0.85 | RORC (0.42) | PTGER1IDH1 | |
| SCHEMBL15057366 | 0.85 | EPHX2 (0.41) | PTGER1CACNA1HCNR1IDH1 | |
| SCHEMBL20629014 | 0.77 | PTGER1 (0.37) | PTGER1CACNA1H | |
| SCHEMBL15057344 | 0.76 | ALKBH1 (0.40) | PTGER1TACR1 | |
| SCHEMBL15057507 | 0.76 | EPHX2 (0.38) | PTGER1IDH1 | |
| SCHEMBL15057775 | 0.76 | PLA2G4A (0.43) | PTGER1 | |
| SCHEMBL15054725 | 0.76 | FOS (0.41) | PTGER1TACR1 | |
| SCHEMBL15057921 | 0.74 | FOS (0.38) | PTGER1 | |
| SCHEMBL15057589 | 0.73 | PLA2G4A (0.42) | PTGER1 | |
| SCHEMBL20628807 | 0.73 | PTGER1 (0.37) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-B1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN INC (US) | 2020-12-02 | — | — | EP | disclosed |