Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630860 | 0.94 | ADRA1D (0.42) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12528167 | 0.93 | CASP1 (0.35) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12495141 | 0.93 | CASP1 (0.43) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL20631312 | 0.88 | ADRA1D (0.43) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12495579 | 0.86 | ADRA1D (0.47) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12528173 | 0.85 | ADRA1D (0.38) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12527288 | 0.82 | ADRA1D (0.40) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL20631468 | 0.82 | ADRA1A (0.48) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12494765 | 0.80 | ADRA1D (0.48) | CASP1CASP7ADRA1DADRA1AADRA1B | |
| SCHEMBL12495445 | 0.80 | CYP19A1 (0.53) | CASP1CASP7MAPTLMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683714-B1 | II (PI)-CONJUGATED FLUOROIONOPHORES AND METHOD FOR DETERMINING AN ALKALI ION | UNIV POTSDAM (DE) | 2019-01-09 | — | — | EP | disclosed |