Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13454840 | 0.79 | GRM5 (0.45) | — | |
| SCHEMBL5485323 | 0.67 | GPR3 (0.36) | — | |
| SCHEMBL24442281 | 0.63 | MAPT (0.56) | — | |
| SCHEMBL9014737 | 0.62 | TYMS (0.40) | TYMS | |
| SCHEMBL211099 | 0.61 | — | — | |
| SCHEMBL15325030 | 0.61 | — | — | |
| SCHEMBL207566 | 0.61 | — | — | |
| SCHEMBL31447514 | 0.61 | RAB9A (0.38) | TYMS | |
| SCHEMBL571181 | 0.61 | RAB9A (0.38) | TYMS | |
| SCHEMBL4516223 | 0.61 | AKR1C3 (0.33) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997658-B | Triazole derivatives as hypoxia imaging agents | 法国国家科研中心 | 2024-01-26 | — | — | CN | disclosed |
| US-11135319-B2 | Compounds useful as imaging agents of hypoxia | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-10-05 | — | — | US | disclosed |
| US-11135319-B2 | Compounds useful as imaging agents of hypoxia | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-10-05 | — | — | US | disclosed |
| US-20200171178-A1 | COMPOUNDS USEFUL AS IMAGING AGENTS OF HYPOXIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-06-04 | — | — | US | disclosed |
| US-20200171178-A1 | COMPOUNDS USEFUL AS IMAGING AGENTS OF HYPOXIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-06-04 | — | — | US | disclosed |
| CN-110997658-A | Triazole derivatives as hypoxia imaging agents | 法国国家科研中心 | 2020-04-10 | — | — | CN | disclosed |
| WO-2019008119-A1 | TRIAZOLE DERIVATIVES USED AS A HYPOXIA IMAGING AGENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-01-10 | — | — | WO | disclosed |
| US-9422225-B2 | Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135319-B2 | Compounds useful as imaging agents of hypoxia | HIF1AN, HIF1A, HYOU1 | TYMS 861/4885 |
| US-20200171178-A1 | COMPOUNDS USEFUL AS IMAGING AGENTS OF HYPOXIA | HIF1AN, HIF1A, HYOU1 | TYMS 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.