Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432052 | 0.91 | ALDH1A1 (0.41) | TYMSDRD2DRD3PNMTSLC6A4 | |
| SCHEMBL8669783 | 0.91 | TSHR (0.40) | TYMSDRD2DRD3PNMTSLC6A4 | |
| SCHEMBL6651818 | 0.82 | CYP2A6 (0.48) | TYMSDRD2DRD3PNMTSLC6A4 | |
| SCHEMBL31447514 | 0.78 | RAB9A (0.38) | TYMSSLC6A4HDAC8CA12CA1 | |
| SCHEMBL571181 | 0.78 | RAB9A (0.38) | TYMSSLC6A4HDAC8CA12CA1 | |
| SCHEMBL25404130 | 0.78 | DRD2 (0.71) | DRD2DRD3PNMT | |
| SCHEMBL19533104 | 0.78 | PNMT (0.71) | DRD2DRD3PNMT | |
| SCHEMBL4516223 | 0.78 | AKR1C3 (0.33) | TYMSDRD2DRD3PNMTSLC6A4 | |
| SCHEMBL6979260 | 0.74 | GRM5 (0.62) | TYMSGRM5 | |
| SCHEMBL11810176 | 0.74 | SRD5A1 (0.47) | TYMSDRD2DRD3SLC6A4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567835-A | Preparation of a vinylsiloxane-benzocylobutene from a hydrolyzable vinylsilane-benzocylobutene | THE DOW CHEMICAL COMPANY (US) | 1996-10-22 | — | — | US | disclosed |