Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631699 | 0.98 | CYP11B2 (0.35) | CYP11B2HDAC2CNR1USP30BRAF | |
| SCHEMBL20632169 | 0.89 | CYP11B2 (0.35) | CYP11B2CNR1USP30BRAFMTOR | |
| SCHEMBL20633345 | 0.89 | NPC1 (0.40) | CYP11B2CNR1BRAFTEK | |
| SCHEMBL20631659 | 0.87 | GRIN1 (0.32) | CNR1 | |
| SCHEMBL20631589 | 0.86 | PHGDH (0.35) | BRAF | |
| SCHEMBL20632750 | 0.85 | GRIN1 (0.37) | CNR1BRAF | |
| SCHEMBL20631494 | 0.85 | MET (0.37) | CYP11B2CNR1USP30MTORLRRK2 | |
| SCHEMBL20632104 | 0.85 | HTR2A (0.32) | LRRK2 | |
| SCHEMBL20632592 | 0.84 | CYP1A2 (0.38) | CYP11B2 | |
| SCHEMBL20631471 | 0.83 | BCL6 (0.33) | CYP11B2HDAC2USP30MTORLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |