Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20632750 | 0.94 | GRIN1 (0.37) | CSF1RKITGRIN1GRIN2BRAF1 | |
| SCHEMBL20632213 | 0.92 | GRIN1 (0.31) | GRIN1GRIN2B | |
| SCHEMBL20632922 | 0.91 | KDM4E (0.36) | NTRK1KDM1AFYNCSF1RKIT | |
| SCHEMBL20631659 | 0.87 | GRIN1 (0.32) | GRIN1GRIN2BCA9 | |
| SCHEMBL20633408 | 0.86 | CYP11B2 (0.35) | BRAF | |
| SCHEMBL20632592 | 0.85 | CYP1A2 (0.38) | KDM4EMAPTKCNH2MEN1KMT2A | |
| SCHEMBL20631699 | 0.85 | CYP11B2 (0.35) | BRAF | |
| SCHEMBL20633005 | 0.84 | LMNA (0.38) | NTRK1KDM1AFYNRAF1BRAF | |
| SCHEMBL20633441 | 0.84 | FYN (0.39) | KDM1AFYNCSF1RKITRAF1 | |
| SCHEMBL20632995 | 0.83 | GRIN1 (0.31) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |