Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 2/20 | 0.31 |
| ▸ | PYGB | P11216 | 1/20 | 0.31 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21371647 | 0.86 | — | — | |
| SCHEMBL18420875 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTT | |
| SCHEMBL16868373 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HTT | |
| SCHEMBL23651597 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTT | |
| SCHEMBL17082979 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTT | |
| SCHEMBL239415 | 0.77 | CRBN (0.41) | NEK2CRBN | |
| Ammonia Solution, Strong SCHEMBL1763719 | 0.76 | CRBN (0.40) | NEK2CRBN | |
| Hydrochloric Acid SCHEMBL8809373 | 0.76 | CRBN (0.40) | NEK2CRBN | |
| SCHEMBL24767075 | 0.71 | LMNA (0.31) | — | |
| SCHEMBL23651601 | 0.71 | PDE7A (0.38) | NEK2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352366-B2 | 2-aminoquinazolinone derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-06-07 | — | — | US | disclosed |
| US-20220143020-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20210380598-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-11066425-B1 | Oxo-substituted compound | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| WO-2019009369-A1 | IMINE DERIVATIVE | 大日本住友製薬株式会社 | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066425-B1 | Oxo-substituted compound | CYP51A1, OXA1L, O60361 | NEK2 2829/4885ALDH1A1 473/4885HTT 4871/4885 |
| US-20220143020-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | CNKSR1, HAX1, CRKL | NEK2 993/4885ALDH1A1 645/4885HTT 2733/4885 |
| US-20210380598-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | CNKSR1, HAX1, SLC26A3 | NEK2 733/4885ALDH1A1 739/4885HTT 2226/4885 |
| US-11352366-B2 | 2-aminoquinazolinone derivative | CNKSR1, HAX1, SLC26A3 | NEK2 733/4885ALDH1A1 739/4885HTT 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.