SCHEMBL20634846

SCHEMBL20634846

CCCCCC1CCC(c2ccc(OC)cc2-c2cc(OC)ccc2C2CCC(CCCC)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39
MAOB P27338 2/20 0.39
CYP1A1 P04798 1/20 0.38
GRM2 Q14416 2/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
NQO2 P16083 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
DRD2 P14416 4/20 0.36
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
DRD3 P35462 3/20 0.35
DRD4 P21917 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19993026 0.92 SIGMAR1 (0.38) HTR2AMAOBNPC1RAB9AGAA
SCHEMBL20634847 0.88 CHRNB2 (0.36) MAOBNPC1RAB9AGAAMAPT
SCHEMBL19722481 0.85 OPRL1 (0.41) HTR2AGRM2
SCHEMBL19722110 0.82 OPRL1 (0.39) HTR2AGRM2
SCHEMBL7910586 0.79 DRD2 (0.54) GRM2RAB9AGAAMAPTDRD2
SCHEMBL7910589 0.79 DRD2 (0.54) GRM2RAB9AGAAMAPTDRD2
SCHEMBL12739755 0.78 MEN1 (0.37) HTR2AMAOBCNR1CNR2MEN1
SCHEMBL11140737 0.78 SLC6A4 (0.44) NPC1RAB9AGAAMAPTDRD2
SCHEMBL11140732 0.78 SLC6A4 (0.44) NPC1RAB9AGAAMAPTDRD2
SCHEMBL6056694 0.78 HTR2A (0.45) HTR2AMAOBCYP1A1GRM2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907864-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THIS COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2019-01-09 EP disclosed