SCHEMBL24922841

SCHEMBL24922841

CC(C)c1cc(F)cc(C(C)C)c1NC(=O)NS(=O)(=O)C1CCN(CC(F)(F)F)CC1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 2/20 0.39
▸ NLRP3 Q96P20 4/20 0.38
▸ CXCR2 P25025 1/20 0.37
▸ GSTO1 P78417 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20635805 0.95 KAT6A (0.41) KAT6ANLRP3CXCR2GSTO1
SCHEMBL20636162 0.91 NLRP3 (0.46) KAT6ANLRP3CXCR2GSTO1
SCHEMBL22433299 0.90 GSTO1 (0.37) NLRP3GSTO1
SCHEMBL22433560 0.89 KAT6A (0.43) KAT6ANLRP3GSTO1
SCHEMBL20636166 0.89 MEN1 (0.46) —
SCHEMBL22433572 0.89 RECQL (0.41) NLRP3GSTO1
SCHEMBL22433304 0.87 DRD2 (0.37) NLRP3GSTO1
SCHEMBL22433382 0.87 SOAT1 (0.39) —
SCHEMBL20635811 0.86 NLRP3 (0.45) KAT6ANLRP3CXCR2GSTO1
SCHEMBL20636155 0.85 GSTO1 (0.39) NLRP3GSTO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LTD (IE) 2023-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230037255-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS NLRP3, NOD1, NLRP1 KAT6A 3681/4885NLRP3 1/4885CXCR2 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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