Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104233 | 0.94 | ALDH1A1 (0.47) | EPHX2ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL10078425 | 0.88 | KIF11 (0.45) | ALDH1A1TSHRSLC6A4 | |
| SCHEMBL508197 | 0.88 | SLC6A4 (0.49) | EPHX2ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL508826 | 0.83 | CYP2D6 (0.41) | ALDH1A1TSHRSLC6A4DAOBCHE | |
| SCHEMBL508827 | 0.83 | CYP2D6 (0.41) | ALDH1A1TSHRSLC6A4DAOBCHE | |
| SCHEMBL28780452 | 0.82 | EPHX2 (0.50) | EPHX2LTA4HALDH1A1TSHRMMP2 | |
| SCHEMBL5885219 | 0.82 | ST14 (0.48) | LTA4HALDH1A1TSHRMAPT | |
| SCHEMBL2056132 | 0.82 | TSHR (0.53) | EPHX2LTA4HALDH1A1TSHRMMP2 | |
| SCHEMBL6002645 | 0.80 | EPHX2 (0.44) | EPHX2LTA4HALDH1A1TSHRMMP2 | |
| SCHEMBL922517 | 0.80 | ST14 (0.61) | EPHX2LTA4HALDH1A1TSHRMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781177-B2 | Pyridine compound and use thereof | NIPPON SODA CO., LTD. (JP) | 2020-09-22 | — | — | US | disclosed |
| US-20190071403-A1 | PYRIDINE COMPOUND AND USE THEREOF | NIPPON SODA CO., LTD. (JP) | 2019-03-07 | — | — | US | disclosed |
| EP-3428151-A1 | PYRIDINE COMPOUND AND USE THEREOF | Nippon Soda Co., Ltd. (JP) | 2019-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781177-B2 | Pyridine compound and use thereof | NOX1, NOXO1, NOX4 | EPHX2 2286/4885LTA4H 1110/4885ALDH1A1 923/4885 |
| US-20190071403-A1 | PYRIDINE COMPOUND AND USE THEREOF | NOX1, NOXO1, NOX4 | EPHX2 2286/4885LTA4H 1110/4885ALDH1A1 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.