Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960120 | 0.82 | SMN1; SMN2 (0.45) | MT-CO2TRPA1CHRM1LMNASLC6A2 | |
| SCHEMBL8960117 | 0.82 | SMN1; SMN2 (0.45) | MT-CO2TRPA1CHRM1LMNASLC6A2 | |
| SCHEMBL8321938 | 0.81 | HPGD (0.47) | MT-CO2TDP1TP53LMNAGAA | |
| SCHEMBL12606507 | 0.79 | ALDH1A1 (0.50) | MT-CO2TDP1ALDH1A1PTGS2HPGD | |
| SCHEMBL28968847 | 0.79 | MT-CO2 (0.51) | MT-CO2TDP1LMNAALDH1A1GAA | |
| SCHEMBL16219339 | 0.78 | MT-CO2 (0.41) | MT-CO2PTGS1PTGS2HPGD | |
| SCHEMBL2063733 | 0.78 | LPAR1 (0.50) | LPAR1 | |
| SCHEMBL10174511 | 0.77 | SMN1; SMN2 (0.44) | MT-CO2ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL31517035 | 0.77 | GABRA1 (0.52) | MT-CO2LMNAALDH1A1POLBPTGS1 | |
| SCHEMBL1345444 | 0.77 | GABRA1 (0.52) | MT-CO2LMNAALDH1A1POLBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |