Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | APP | P05067 | 2/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214917 | 1.00 | TDP1 (0.84) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5097 | 0.92 | — | — | |
| SCHEMBL8526630 | 0.92 | TDP1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL357435 | 0.89 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL3947579 | 0.89 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrochloric Acid SCHEMBL208637 | 0.89 | ALDH1A1 (1.00) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Ethane SCHEMBL11031442 | 0.89 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL21840887 | 0.89 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Methane SCHEMBL22289589 | 0.89 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5601373 | 0.89 | TDP1 (0.94) | TDP1MAPK1ALDH1A1CYP3A4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898173-B | Method for preparing amide compound by photocatalytic organic amine | 湖南中医药大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-112898173-A | Method for preparing amide compound by photocatalytic organic amine | 湖南中医药大学 | 2021-06-04 | — | — | CN | disclosed |
| US-6506937-B2 | Used as antiarrhythmics | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-01-14 | — | — | US | disclosed |
| US-20020058838-A1 | Substituted benzenesulfonylureas and -thioureas-processes for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT | 2002-05-16 | — | — | US | disclosed |
| US-6335467-B1 | INTERMEDIATES FOR ANTIARRHYTHMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| US-6090981-A | ANTIARRHYTHMICS. | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-07-18 | — | — | US | disclosed |
| US-5776980-A | Substituted benzenesulfonylureas and -thioureas-process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5574069-A | ANTIARRHYTHMIA | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058838-A1 | Substituted benzenesulfonylureas and -thioureas-processes for their preparation and their use as pharmaceuticals | KCNH1, KCNH2, KCNH3 | TDP1 669/4885MAPK1 1045/4885ALDH1A1 830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.