SCHEMBL20640249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20653722	0.83	KMT2A (0.43)	KMT2ASLC6A4SLC6A3SLC6A2CCR2
	SCHEMBL22832485	0.82	KMT2A (0.42)	KMT2ASLC6A4SLC6A3SLC6A2ALDH1A1
	SCHEMBL16701145	0.81	OPRM1 (0.35)	SLC6A4SLC6A3SLC6A2ALDH1A1LRRK2
	SCHEMBL13163320	0.80	OPRM1 (0.41)	KMT2AALDH1A1OPRM1OPRL1
	SCHEMBL10526309	0.79	KDM1A (0.46)	KMT2ASLC6A4SLC6A3SLC6A2KDM1A
	SCHEMBL626449	0.76	KDM1A (0.43)	KMT2ASLC6A4SLC6A3SLC6A2KDM1A
	SCHEMBL1018956	0.76	SLC6A4 (0.46)	KMT2ASLC6A4SLC6A3SLC6A2KDM1A
	SCHEMBL16591230	0.75	KDM1A (0.47)	KMT2ASLC6A4SLC6A3SLC6A2KDM1A
	SCHEMBL1020648	0.74	SLC6A4 (0.49)	KMT2ASLC6A4SLC6A3SLC6A2KDM1A
	SCHEMBL16701036	0.73	HSD11B1 (0.37)	KMT2AALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.