SCHEMBL206408

SCHEMBL206408

N[C@H]([C]=O)Cc1ccc(OP(=O)(O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 5/20 0.45
ANPEP P15144 2/20 0.45
SRC P12931 1/20 0.43
BLM P54132 1/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
INPPL1 O15357 2/20 0.39
INPP5A Q14642 2/20 0.39
PLAU P00749 1/20 0.38
GRB2 P62993 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8344068 1.00 LAP3 (0.45) LAP3ANPEPSRCBLMCA1
SCHEMBL7717778 0.82 LAP3 (0.39) LAP3ANPEPCYP2C19SMN1; SMN2PLAU
SCHEMBL21807707 0.80 SLC6A4 (0.58) LAP3ANPEPBLM
SCHEMBL3123300 0.80 SLC6A4 (0.58) LAP3ANPEPBLM
SCHEMBL15720261 0.79 PTPRC (0.56) LAP3ANPEPSRCBLMSMN1; SMN2
SCHEMBL15720264 0.79 PTPRC (0.56) LAP3ANPEPSRCBLMSMN1; SMN2
Phosphoric Acid SCHEMBL28984077 0.78 SLC7A5 (0.49) LAP3ANPEPCYP2C19
SCHEMBL1152 0.77 PTPRC (0.57) LAP3ANPEPSRCBLMSMN1; SMN2
SCHEMBL3626587 0.77 PTPRC (0.57) LAP3ANPEPSRCBLMSMN1; SMN2
SCHEMBL273663 0.77 PTPRC (0.57) LAP3ANPEPSRCBLMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016042137-A1 METHOD FOR DIAGNOSING MYELOPROLIFERATIVE CHRONIC MYELOMONOCYTIC LEUKEMIA OR UNCLASSIFIED MYELOPROLIFERATIVE MYELODYSPLASTIC NEOPLASM INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2016-03-24 WO claimed
EP-2387586-B1 ANTIBODIES AGAINST HUMAN EPO RECEPTOR HOFFMANN LA ROCHE (CH) 2014-12-17 EP claimed
US-20120122120-A1 ANTIBODIES AGAINST HUMAN EPO RECEPTOR HOFFMANN-LA ROCHE INC. (US) 2012-05-17 US claimed
EP-2387586-A2 ANTIBODIES AGAINST HUMAN EPO RECEPTOR F. Hoffmann-La Roche AG (CH) 2011-11-23 EP claimed
WO-2010081679-A2 ANTIBODIES AGAINST HUMAN EPO RECEPTOR F. HOFFMANN-LA ROCHE AG (CH) 2010-07-22 WO claimed
US-20100035793-A1 Modulators AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-02-11 US claimed
EP-1915162-A4 MODULATORS AGENCY SCIENCE TECH & RES (SG) 2009-08-26 EP claimed
EP-1915162-A1 MODULATORS Agency for Science, Technology and Research (SG) 2008-04-30 EP claimed
WO-2007013852-A1 MODULATORS AGENCY FOR SCIENCE, TECHNOLOGY & RESEARCH (SG) 2007-02-01 WO claimed
US-20030065146-A1 Monomeric diols, phosphate linked oligomers formed therefrom and processes for preparing COOK PHILLIP D (US) 2003-04-03 US claimed
EP-0739351-A4 MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM ISIS PHARMACEUTICALS INC (US) 1998-10-21 EP claimed
US-5691305-A Bone implant composition comprising a porous matrix, bone growth promoter proteins, and phosphotyrosyl protein phosphatase inhibitor BAYLINK DAVID J (US) 1997-11-25 US claimed
EP-0739351-A1 MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM ISIS PHARMACEUTICALS, INC. (US) 1996-10-30 EP claimed
WO-1995018820-A1 MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM ISIS PHARMACEUTICALS, INC. (US) 1995-07-13 WO claimed
EP-0614530-A4 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS. CORNELL RES FOUNDATION INC (US) 1995-06-07 EP claimed
EP-0614530-A1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RESEARCH FOUNDATION, INC. (US) 1994-09-14 EP claimed
WO-1993010460-A1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RESEARCH FOUNDATION, INC. (US) 1993-05-27 WO claimed
EP-0527184-A1 PHOSPHORAMIDITE DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF IN THE INCORPORATION OF REPORTER GROUPS ON SYNTHETIC OLIGONUCLEOTIDES. AMERSHAM INT PLC (GB) 1993-02-17 EP claimed
US-4710469-A DEPHOSPHORIZATING KINASE; ANTITUMOR AND-DIABETIC AGENTS; ATHEROSCLEROSIS MERCK & CO., INC. (US) 1987-12-01 US claimed
EP-0245979-A2 Novel phosphotyrosyl protein phosphatase MERCK & CO. INC. (US) 1987-11-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065146-A1 Monomeric diols, phosphate linked oligomers formed therefrom and processes for preparing BPGM, PPIP5K2, PGM2 LAP3 3226/4885ANPEP 1959/4885SRC 3287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.