SCHEMBL2065115

SCHEMBL2065115

C/C=C\c1ccc2nc(Cl)cn2n1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.37
APLNR P35414 1/20 0.34
DYRK1A Q13627 1/20 0.33
AHR P35869 2/20 0.33
MAP4K4 O95819 1/20 0.33
PRKACA P17612 1/20 0.33
CDK8 P49336 1/20 0.33
MAPK14 Q16539 1/20 0.33
LRRK2 Q5S007 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065116 1.00 PDE10A (0.37) PDE10AAPLNRDYRK1AAHRMAP4K4
SCHEMBL2065778 0.80 AHR (0.36) APLNRDYRK1AAHRMAP4K4PRKACA
SCHEMBL2066604 0.80 APLNR (0.34) APLNRDYRK1AAHRMAP4K4PRKACA
SCHEMBL2065779 0.80 AHR (0.36) APLNRDYRK1AAHRMAP4K4PRKACA
SCHEMBL2066605 0.80 APLNR (0.34) APLNRDYRK1AAHRMAP4K4PRKACA
SCHEMBL2066344 0.79 PDE10A (0.36) PDE10ADYRK1AAHR
SCHEMBL756100 0.74 KDM4E (0.50) PDE10ADYRK1AAHR
SCHEMBL3086869 0.73 KDM4E (0.44) PDE10ADYRK1AAHRLRRK2
SCHEMBL3342789 0.69 PDE10A (0.39) PDE10ADYRK1AAHR
SCHEMBL2066163 0.69 PDE10A (0.50) PDE10ADYRK1AAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE10A 3486/4885APLNR 4557/4885DYRK1A 1927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.