SCHEMBL2065137

SCHEMBL2065137

CCCC(O)C(O)(O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.42
AKR1A1 P14550 1/20 0.42
CHRM3 P20309 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
ADRA1A P35348 1/20 0.42
HRH1 P35367 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ACACB O00763 1/20 0.36
ACACA Q13085 1/20 0.36
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
NFKB1 P19838 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GPR84 Q9NQS5 7/20 0.35
FFAR1 O14842 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3299285 0.86 CA2 (0.43) ACACBACACANFKB1GPR84FFAR1
SCHEMBL18322324 0.83 GPR84 (0.53) ACACBACACANFKB1GPR84FFAR1
SCHEMBL9297272 0.83 GPR84 (0.53) ACACBACACANFKB1GPR84FFAR1
SCHEMBL325989 0.83 GPR84 (0.53) ACACBACACANFKB1GPR84FFAR1
SCHEMBL7148025 0.83 GPR84 (0.53) ACACBACACANFKB1GPR84FFAR1
SCHEMBL965732 0.82 CHRM1 (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6686309 0.81 GPR84 (0.52) ACACBACACANFKB1GPR84FFAR1
Ammonia Solution, Strong SCHEMBL10519337 0.81 GPR84 (0.52) ACACBACACANFKB1GPR84FFAR1
SCHEMBL2784984 0.80 TSHR (0.43) CHRM1ADRA1AACACBACACATSHR
SCHEMBL28094738 0.79 CHRM1 (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020239083-A1 AEROSOL GENERATION OR SMOKING SYSTEM, OR ELECTRONIC CIGARETTE AND DEVICE THEREOF 钟术光 2020-12-03 WO claimed
EP-0583171-B1 (3R,5S)-3,5,6-trihydroxyhexanoic acid derivatives and methods for their production TAKASAGO PERFUMERY CO LTD (JP) 1998-11-11 EP claimed
EP-0374922-B1 Process for the production of 3,5,6-trihydroxyhexanoic acid derivative KANEGAFUCHI CHEMICAL IND (JP) 1995-06-28 EP claimed
EP-0583171-A2 (3R,5S)-3,5,6-trihydroxyhexanoic acid derivatives and methods for their production Takasago International Corporation (JP) 1994-02-16 EP claimed
US-4983759-A Process for the production of 3,5,6-trihydroxyhexanoic acid derivative KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-08 US claimed
EP-0374922-A2 Process for the production of 3,5,6-trihydroxyhexanoic acid derivative Kanegafuchi Chemical Industry Co., Ltd. (JP) 1990-06-27 EP claimed
US-20250275993-A1 GLYCOSYLATION INHIBITORS AS THERAPEUTICS FOR STROKE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-04 US disclosed
WO-2020239083-A1 AEROSOL GENERATION OR SMOKING SYSTEM, OR ELECTRONIC CIGARETTE AND DEVICE THEREOF 钟术光 2020-12-03 WO disclosed
US-8148550-B2 selected from fluvastatin, rosuvastatin, cerivastatin, glenvastatin or atorvastatin, by reduction or lactonization of chemical intermediate compounds, then hydrogenation, decyclization and deprotection of hydroxy groups RATIOPHARM GMBH (DE) 2012-04-03 US disclosed
EP-1682527-B1 METHOD FOR THE PRODUCTION OF STATINS RATIOPHARM GMBH (DE) 2011-08-24 EP disclosed
US-20080249306-A1 Method for the Production of Statins RATIOPHARM GMBH (DE) 2008-10-09 US disclosed
EP-1888600-A2 METHOD FOR THE PRODUCTION OF STATINS Ratiopharm GmbH (DE) 2008-02-20 EP disclosed
US-20070093660-A1 Method for the production of statins RATIOPHARM GMBH (DE) 2007-04-26 US disclosed
EP-1288213-A4 PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES KANEKA CORP (JP) 2004-03-31 EP disclosed
EP-1288213-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2003-03-05 EP disclosed
EP-1288213-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2003-03-05 EP disclosed
WO-2001094337-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2-[6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2001-12-13 WO disclosed
EP-0374922-B1 Process for the production of 3,5,6-trihydroxyhexanoic acid derivative KANEGAFUCHI CHEMICAL IND (JP) 1995-06-28 EP disclosed
US-4983759-A Process for the production of 3,5,6-trihydroxyhexanoic acid derivative KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-01-08 US disclosed
EP-0374922-A2 Process for the production of 3,5,6-trihydroxyhexanoic acid derivative Kanegafuchi Chemical Industry Co., Ltd. (JP) 1990-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093660-A1 Method for the production of statins HMGCR, CYP11A1, CYP51A1 CHRM1 1090/4885AKR1A1 111/4885CHRM3 2792/4885
US-20080249306-A1 Method for the Production of Statins HMGCR, COASY, PCSK9 CHRM1 4602/4885AKR1A1 167/4885CHRM3 3765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.