Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162385 | 0.92 | MAPT (0.60) | MAPTALDH1A1TDP1LMNAALOX15 | |
| Avobenzone SCHEMBL6595907 | 0.86 | ALDH1A1 (0.72) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL2268368 | 0.82 | MAPT (0.47) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL4197237 | 0.82 | CES2 (0.69) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL10975203 | 0.80 | MAPT (0.51) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL9353462 | 0.79 | MAPT (0.66) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL4663944 | 0.79 | MAPT (0.43) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL15562904 | 0.77 | CES2 (0.62) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL3098687 | 0.77 | MAPT (0.59) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL7733638 | 0.76 | MAPT (0.66) | MAPTALDH1A1TDP1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1895979-B1 | COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO LTD (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-8147854-B2 | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100112017-A1 | Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| WO-2008032883-A2 | COMPOSITION FOR THE PREPARATION OF COSMETICS, COSMETIC, AND METHOD FOR THE PREPARATION OF WATER-CONTAINING COSMETICS | DOW CORNING TORAY CO., LTD. (JP) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028391-A1 | Cosmetics Comprising A Modified Organopolysiloxane | H1-0, H1-2, CHRM1 | MAPT 4481/4885ALDH1A1 1287/4885TDP1 2011/4885 |
| US-20100112017-A1 | Composition For The Preparation of Cosmetics, Cosmetic, and Method For the Preparation Of Water-Containing Cosmetics | H1-0, DEGS1, MSR1 | MAPT 4776/4885ALDH1A1 1448/4885TDP1 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.