Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065160 | 0.92 | MAPT (0.52) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL4197237 | 0.89 | CES2 (0.69) | MAPTALDH1A1L3MBTL1CES2CES1 | |
| SCHEMBL7733638 | 0.83 | MAPT (0.66) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL9353462 | 0.83 | MAPT (0.66) | MAPTALDH1A1TDP1LMNAALOX15 | |
| Avobenzone SCHEMBL5680371 | 0.82 | TDP1 (0.88) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL5206579 | 0.82 | MAPT (0.50) | MAPTALDH1A1TDP1LMNAALOX15 | |
| Avobenzone SCHEMBL19717690 | 0.82 | ALDH1A1 (0.71) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL15562904 | 0.81 | CES2 (0.62) | MAPTALDH1A1LMNAL3MBTL1CES2 | |
| SCHEMBL4411275 | 0.80 | MAPT (0.53) | MAPTALDH1A1TDP1LMNAALOX15 | |
| SCHEMBL324099 | 0.80 | CES2 (0.61) | MAPTALDH1A1LMNAL3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1269981-A2 | Sunscreen compositions containing a dibenzoylmethane derivative | Johnson & Johnson Consumer Companies, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6444195-B1 | MIXTURE OF DIBENZOYLMETHANE AND BENZOPHENONE COMPOUND | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2002-09-03 | — | — | US | disclosed |