Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268368 | 0.97 | MAPT (0.47) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL5771884 | 0.85 | NR1H4 (0.45) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL3795638 | 0.83 | ALDH1A1 (0.60) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL2065160 | 0.79 | MAPT (0.52) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL6130576 | 0.75 | LMNA (0.48) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL7162385 | 0.73 | MAPT (0.60) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL269577 | 0.72 | NPC1 (0.52) | MAPTALDH1A1LMNAALOX15APEX1 | |
| SCHEMBL269013 | 0.72 | LMNA (0.72) | MAPTNR1H4ALDH1A1LMNAALOX15 | |
| SCHEMBL15080783 | 0.72 | MAPT (0.56) | MAPTALDH1A1LMNAMAPK1RAB9A | |
| SCHEMBL9353462 | 0.71 | MAPT (0.66) | MAPTNR1H4ALDH1A1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444195-B1 | MIXTURE OF DIBENZOYLMETHANE AND BENZOPHENONE COMPOUND | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2002-09-03 | — | — | US | claimed |
| US-5587150-A | Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate | L'OREAL (FR) | 1996-12-24 | — | — | US | claimed |
| US-20080260664-A1 | Particles Functionalized with Organic Compounds | MERCK PATENT GMBH (DE) | 2008-10-23 | — | — | US | disclosed |
| EP-1269981-A2 | Sunscreen compositions containing a dibenzoylmethane derivative | Johnson & Johnson Consumer Companies, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6444195-B1 | MIXTURE OF DIBENZOYLMETHANE AND BENZOPHENONE COMPOUND | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2002-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080260664-A1 | Particles Functionalized with Organic Compounds | NCLN, PNN, NCL | MAPT 699/4885NR1H4 3241/4885ALDH1A1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.