Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36267 | 0.92 | MMP1 (0.40) | EPHX1PAOXKDM4EKMT2AMMP1 | |
| Hydrochloric Acid SCHEMBL2066264 | 0.90 | MMP1 (0.39) | EPHX1PAOXKDM4EKMT2AMMP1 | |
| SCHEMBL2066063 | 0.90 | EPHX1 (0.34) | EPHX1PAOXKDM4EKMT2AMMP1 | |
| Chloromethane SCHEMBL4631102 | 0.88 | MMP1 (0.38) | EPHX1PAOXKDM4EKMT2AMMP1 | |
| Acetone SCHEMBL10451495 | 0.88 | MCL1 (0.39) | EPHX1PAOXKDM4EKMT2AMMP1 | |
| Sulfuric Acid SCHEMBL22730070 | 0.84 | MMP1 (0.31) | KMT2AMMP1MMP2MMP3MMP9 | |
| SCHEMBL1067451 | 0.82 | EPHX1 (0.52) | EPHX1DPP7PLA2G2APLA2G4A | |
| Acrylamide SCHEMBL11143542 | 0.81 | ALDH1A1 (0.39) | EPHX1PAOXMMP1MMP2MMP3 | |
| SCHEMBL8775087 | 0.81 | EPHX1 (0.55) | EPHX1KDM4EDPP7PLA2G2APLA2G4A | |
| SCHEMBL994218 | 0.80 | EPHX1 (0.47) | EPHX1MMP2DPP7CYP2C19PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153948-B | Acidic cleaning, disinfecting and germicidal compositions with reduced fogging through the use of high molecular weight water-in-oil emulsion polymers | 埃科莱布美国股份有限公司 | 2021-03-16 | — | — | CN | claimed |
| EP-3164702-B1 | USE OF FLUORESCENT POLYMERS IN MARKING COMPOSITIONS FOR THE DIAGNOSTIC DETERMINATION OF CLEANING PERFORMANCE | ECOLAB USA INC (US) | 2020-12-09 | — | — | EP | claimed |
| CN-110869474-A | Oil-in-water emulsions | 跨瑞丝国际有限责任公司 | 2020-03-06 | — | — | CN | claimed |
| EP-2109441-B1 | POLYSILOXANE BLOCK COPOLYMERS | BASF SE (DE) | 2016-01-27 | — | — | EP | claimed |
| US-8378038-B2 | Polysiloxane block copolymers | BASF SE (DE) | 2013-02-19 | — | — | US | claimed |
| US-20100303750-A1 | POLYSILOXANE BLOCK COPOLYMERS | KOROSKENYI BALINT | 2010-12-02 | — | — | US | claimed |
| EP-2109441-A2 | POLYSILOXANE BLOCK COPOLYMERS | Ciba Holding Inc. (CH) | 2009-10-21 | — | — | EP | claimed |
| US-20080199418-A1 | Polysiloxane block copolymers | BASF SE (DE) | 2008-08-21 | — | — | US | claimed |
| WO-2008095822-A2 | POLYSILOXANE BLOCK COPOLYMERS | CIBA HOLDING INC. (CH) | 2008-08-14 | — | — | WO | claimed |
| CN-115726215-A | Composition and method for making paper | 埃科莱布美国股份有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-110869474-B | Oil-in-water emulsions | 跨瑞丝国际有限责任公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-110730841-B | Reinforcement system and method for the manufacture of a paper web comprising cellulosic fibers | 凯米拉公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114206955-A | Method for controlling production of excess water and aqueous fluids in oil and gas wells | 罗地亚经营管理公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-107849821-B | Aldehyde-functionalized polymers for paper strength and dewatering | 艺康美国股份有限公司 | 2021-12-14 | — | — | CN | disclosed |
| EP-1363957-A4 | CATIONIC LATEX TERPOLYMERS FOR SLUDGE DEWATERING | ONDEO NALCO CO (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1363957-A1 | CATIONIC LATEX TERPOLYMERS FOR SLUDGE DEWATERING | Ondeo Nalco Company (US) | 2003-11-26 | — | — | EP | disclosed |
| US-6627719-B2 | Interpolymer of a cationic monomer, a hydroxyalkyl (meth)acrylate and, optionally, a nonionic monomer | ONDEO NALCO COMPANY | 2003-09-30 | — | — | US | disclosed |
| US-20030060586-A1 | Cationic latex terpolymers for sludge dewatering | ECOLAB USA INC. | 2003-03-27 | — | — | US | disclosed |
| WO-2002060967-A1 | CATIONIC LATEX TERPOLYMERS FOR SLUDGE DEWATERING | ONDEO NALCO COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |
| US-5362614-A | Polyolefin coating, alkyl ketene dimer, anionic colloidal silica | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303750-A1 | POLYSILOXANE BLOCK COPOLYMERS | KRT18, PUF60, SCNN1B | ADRA1A 4154/4885EPHX1 4116/4885PAOX 1042/4885 |
| US-20080199418-A1 | Polysiloxane block copolymers | KRT18, PUF60, SCNN1B | ADRA1A 4154/4885EPHX1 4116/4885PAOX 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.