Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26025883 | 0.93 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL20637955 | 0.86 | ALDH1A1 (0.37) | ALDH1A1SCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL26025783 | 0.79 | ALDH1A1 (0.35) | ALDH1A1SCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL5029937 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL20653008 | 0.75 | — | — | |
| SCHEMBL20652992 | 0.74 | TDP1 (0.38) | ALDH1A1CYP3A4TSHRNFKB1MAOA | |
| SCHEMBL20653228 | 0.73 | — | — | |
| SCHEMBL28204825 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL20637965 | 0.72 | ALDH1A1 (0.35) | ALDH1A1SCN4ALMNACYP1A2CYP3A4 | |
| SCHEMBL5029779 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731932-B2 | Silicon-containing compositions and their methods of use | ADITYA BIRLA CHEMICALS (USA), INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20220356145-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | ADITYA BIRLA CHEMICALS (USA) LLC | 2022-11-10 | — | — | US | disclosed |
| US-10919839-B2 | Silicon-containing compositions and their methods of use | ADITYA BIRLA CHEMICALS (USA) LLC (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190016870-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | ADITYA BIRLA CHEMICALS (USA), INC. | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919839-B2 | Silicon-containing compositions and their methods of use | SRM, REV1, RER1 | ALDH1A1 3388/4885SCN4A 4168/4885LMNA 2224/4885 |
| US-20220356145-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | SRM, REV1, RER1 | ALDH1A1 3388/4885SCN4A 4168/4885LMNA 2224/4885 |
| US-11731932-B2 | Silicon-containing compositions and their methods of use | SRM, REV1, RER1 | ALDH1A1 3388/4885SCN4A 4168/4885LMNA 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.