Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470582 | 0.80 | TDP1 (0.52) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL292991 | 0.80 | TDP1 (0.52) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL11164498 | 0.80 | TDP1 (0.52) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL20653025 | 0.79 | MAPT (0.50) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL20643732 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL25640383 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL12012134 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL6832871 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL20505766 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1NPC1RAB9A | |
| SCHEMBL6141125 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTMAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919839-B2 | Silicon-containing compositions and their methods of use | ADITYA BIRLA CHEMICALS (USA) LLC (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190016870-A1 | SILICON-CONTAINING COMPOSITIONS AND THEIR METHODS OF USE | ADITYA BIRLA CHEMICALS (USA), INC. | 2019-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919839-B2 | Silicon-containing compositions and their methods of use | SRM, REV1, RER1 | ALDH1A1 3388/4885MAPT 2607/4885MAPK1 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.