Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19427420 | 0.93 | DRD2 (0.55) | DRD2DRD4KDM1ABCHEKDM4E | |
| SCHEMBL2065898 | 0.93 | DRD2 (0.55) | DRD2DRD4KDM1ABCHEKDM4E | |
| Water SCHEMBL9452384 | 0.91 | DRD2 (0.54) | DRD2DRD4KDM1ABCHEKDM4E | |
| Formic Acid SCHEMBL28231178 | 0.88 | DRD2 (0.36) | DRD2DRD4KDM1ABCHEKDM4E | |
| Formic Acid SCHEMBL28861710 | 0.88 | DRD2 (0.36) | DRD2DRD4KDM1ABCHEKDM4E | |
| Formic Acid SCHEMBL2065536 | 0.84 | BCHE (0.41) | BCHEKDM4EMAPTPKMMEN1 | |
| SCHEMBL2065442 | 0.80 | SLC22A1 (0.35) | DRD2DRD4KDM1ABCHEKDM4E | |
| SCHEMBL23115288 | 0.79 | SLC22A1 (0.55) | KDM1AHTR2AHTR2CADRB2 | |
| SCHEMBL23115291 | 0.79 | SLC22A1 (0.55) | KDM1AHTR2AHTR2CADRB2 | |
| SCHEMBL23135179 | 0.79 | SLC22A1 (0.55) | KDM1AHTR2AHTR2CADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148527-B1 | Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline | Divi's Laboratories, Ltd. (IN) | 2012-04-03 | — | — | US | claimed |