Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 10/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656231 | 0.88 | CNR2 (0.34) | CNR2ACACBP2RX3MDM2 | |
| SCHEMBL20655944 | 0.84 | FFAR4 (0.34) | CNR2ACACBP2RX3MDM2PDE6D | |
| SCHEMBL24095547 | 0.83 | MDM2 (0.35) | CNR2P2RX3MDM2PDE6D | |
| SCHEMBL20656040 | 0.78 | FFAR4 (0.35) | CNR2ACACBMDM2 | |
| SCHEMBL24095548 | 0.78 | FFAR4 (0.36) | CNR2MDM2 | |
| SCHEMBL24095550 | 0.77 | MDM2 (0.37) | MDM2 | |
| SCHEMBL24095598 | 0.73 | MDM2 (0.32) | CNR2ACACBP2RX3MDM2 | |
| SCHEMBL20656239 | 0.72 | CNR1 (0.32) | CNR2ACACBMDM2 | |
| SCHEMBL24095601 | 0.70 | P2RX3 (0.35) | P2RX3MDM2 | |
| SCHEMBL22111440 | 0.69 | P2RX3 (0.35) | P2RX3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |