Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20655944 | 0.93 | FFAR4 (0.34) | FFAR4GPBAR1MDM2CNR2 | |
| SCHEMBL20656040 | 0.93 | FFAR4 (0.35) | FFAR4GPBAR1MDM2CNR2ALOX5AP | |
| SCHEMBL24095550 | 0.90 | MDM2 (0.37) | GPBAR1MDM2 | |
| SCHEMBL20656239 | 0.85 | CNR1 (0.32) | FFAR4GPBAR1MDM2CNR2 | |
| SCHEMBL24095547 | 0.85 | MDM2 (0.35) | MDM2CNR2GPR6 | |
| SCHEMBL20656015 | 0.78 | CNR2 (0.34) | MDM2CNR2 | |
| SCHEMBL20656231 | 0.77 | CNR2 (0.34) | MDM2CNR2 | |
| SCHEMBL24095601 | 0.76 | P2RX3 (0.35) | MDM2 | |
| SCHEMBL24095593 | 0.74 | P2RX3 (0.39) | CNR2 | |
| SCHEMBL24095546 | 0.74 | GPBAR1 (0.41) | FFAR4GPBAR1MDM2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |