Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20655944 | 0.88 | FFAR4 (0.34) | CNR2ACACBGPBAR1FFAR4MDM2 | |
| SCHEMBL20656040 | 0.86 | FFAR4 (0.35) | CNR2ACACBGPBAR1FFAR4MDM2 | |
| SCHEMBL24095550 | 0.86 | MDM2 (0.37) | GPBAR1MDM2 | |
| SCHEMBL24095548 | 0.85 | FFAR4 (0.36) | CNR2GPBAR1FFAR4MDM2 | |
| SCHEMBL24095547 | 0.80 | MDM2 (0.35) | CNR1CNR2MDM2 | |
| SCHEMBL24095601 | 0.76 | P2RX3 (0.35) | MDM2 | |
| SCHEMBL20656231 | 0.76 | CNR2 (0.34) | CNR2ACACBMDM2 | |
| SCHEMBL24095593 | 0.74 | P2RX3 (0.39) | CNR2 | |
| SCHEMBL20656234 | 0.73 | P2RX3 (0.33) | GPBAR1FFAR4 | |
| SCHEMBL20656015 | 0.72 | CNR2 (0.34) | CNR2ACACBMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |