Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | PDE6D | O43924 | 4/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20655944 | 0.91 | FFAR4 (0.34) | MDM2CNR2PDE6DP2RX3 | |
| SCHEMBL20656040 | 0.86 | FFAR4 (0.35) | MDM2CNR2DRD2HTR2A | |
| SCHEMBL24095548 | 0.85 | FFAR4 (0.36) | MDM2CNR2GPR6 | |
| SCHEMBL24095550 | 0.83 | MDM2 (0.37) | MDM2 | |
| SCHEMBL20656015 | 0.83 | CNR2 (0.34) | MDM2CNR2PDE6DP2RX3 | |
| SCHEMBL20656239 | 0.80 | CNR1 (0.32) | MDM2CNR2CNR1 | |
| SCHEMBL24095601 | 0.77 | P2RX3 (0.35) | MDM2P2RX3 | |
| SCHEMBL20656231 | 0.77 | CNR2 (0.34) | MDM2CNR2P2RX3 | |
| SCHEMBL24095593 | 0.73 | P2RX3 (0.39) | CNR2P2RX3 | |
| SCHEMBL24095600 | 0.72 | CNR2 (0.35) | MDM2CNR2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |